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Deflazacort

Deflazacort

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What is it?

Deflazacort is a medication developed for the treatment of Duchenne muscular dystrophy (DMD). This disease is a rare muscle disorder that primarily affects children and young adults. It is caused by a lack of a protein called dystrophin, which is essential for maintaining muscle cell integrity. Deflazacort belongs to a class of drugs called corticosteroids, which are similar to cortisone or steroids. While this medication cannot completely cure the disease, it can improve muscle strength and slow the progression of disability.

Composition

Deflazacorts main component, deflazacort, plays a key role in its therapeutic properties. Its composition is carefully designed to ensure maximum efficacy and safety. It includes the following components:

  • Deflazacort as the main active ingredient;
  • Excipients to ensure drug stability;
  • Components that promote better absorption and distribution in the body.

The development of Deflazacort is based on the careful selection of ingredients, each of which is essential for achieving optimal treatment results. The excipients in the formula maintain stability and ensure effective delivery of the active ingredient to the site of action. This allows the drug to provide a consistent therapeutic effect throughout the entire course of treatment.

How to use?

For maximum effectiveness, Deflazacort should be used as directed by your doctor. This includes both the correct dosage and regularity. The medication can be taken with or without food, making it convenient to use. However, it is important to follow the exact treatment regimen prescribed by your doctor to avoid potential complications and achieve the best results.

When using Deflazacort, it is also important to keep in mind that the dosage is based on the patients weight, especially for children and adolescents. The following is recommended:

  1. The starting dose for adult patients is approximately 0.9 mg/kg taken orally once daily;
  2. For children aged 2 years and older, the dose is usually the same 0.9 mg/kg per day.

Dose adjustments may be necessary due to changes in the patients weight, so regular monitoring by a doctor is essential.

How does it work?

Deflazacorts effects stem from its membership in the corticosteroid class. These substances are known for their ability to reduce inflammation and suppress the immune response. In the case of deflazacort, this leads to improved muscle health in patients with Duchenne muscular dystrophy. The active substance reduces muscle cell breakdown, which in turn contributes to improved overall muscle function.

Furthermore, the drug helps slow the progression of disability, significantly improving patients quality of life. The lack of dystrophin in the muscles of Duchenne muscular dystrophy is a key problem, and deflazacort helps compensate for the effects of this deficiency. Naturally, the drug does not completely solve the problem, but its use can significantly improve the patients condition.

Indications

Deflazacort is prescribed for clearly defined medical indications related to the need to improve muscular health. The drug helps manage specific symptoms associated with Duchenne muscular dystrophy. The main indications for the drug include:

  • Duchenne muscular dystrophy in children aged 2 years and older, as well as in adults;
  • The need to improve muscle strength and endurance;
  • Slowing the progression of disability associated with this disease.

Deflazacort is prescribed only for Duchenne muscular dystrophy and is not used to treat other conditions without a doctors recommendation.

Contraindications

It is important to consider the contraindications when using Deflazacort to avoid unwanted effects. This medication is not recommended for use in the presence of certain conditions that may be worsened by the drug. These contraindications include:

  • Allergy to Deflazacort or other components of the drug;
  • Age under 2 years;
  • Combination with products containing grapefruit due to the risk of adverse effects.

Also, vaccination with live vaccines should be avoided during and after treatment with this medication, as this may lead to the development of serious infections. Contraindications require careful consideration by both the physician and the patient.

Side effects

Like many other medications, Deflazacort can cause side effects that should be considered when prescribing it. Despite its general effectiveness, individual intolerance or the development of certain reactions is possible. The most common side effects include:

  • Weight gain associated with fluid retention;
  • Fluctuations in blood glucose levels, which is important for patients with diabetes;
  • High blood pressure and risk of cardiovascular complications;
  • Effects on mood and psychoemotional state, including irritability or depression.

These reactions do not always occur in all patients, but their possibility should be considered, especially with long-term use. Regular monitoring can help promptly identify and manage any adverse effects.

Frequently asked questions

How much does Deflazacort cost in pharmacies?
Price Deflazacort in different pharmacies in Nigeria it varies.
How to buy Deflazacort without a prescription?
Deflazacort is available over the counter in our pharmacy.

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